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The Effects of Perinatal AZT Exposure on the Acoustic Startle Response in Adult Rats

Friday, September 4, 2009

Susan M. Melnicka, Jeremy Weedonb and Diana L. Dow-Edwards
 
AZT has become the standard medication to prevent the transmission of the human immunodeficiency virus from mother to fetus. The present study was designed to assess the acoustic startle response in adult rats that had been perinatally exposed to AZT. One SR-LAB acoustic startle sound-attenuating chamber (San Diego Instruments) with fan and light recoded the degree of deflection of the platform as the subject responded to the startle stimulus.
 
For more information on this study, please refer to:
 
Neurotoxicology and Teratology

Volume 24, Issue 6, November-December 2002, Pages 773-781


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